FDA: long term use of proton pump inhibitors (Nexium/Prilosec) increase serious bone fracture risk

Yikes! The FDA came out today with a study that says long term use of proton pump inhibitors will greatly increase the risk of fractures on the hip, wrist, and spine.

I’m not a doctor, but I do know getting a fracture on the hip or spine is the “flaming chainsaw with ebola in your face” kind of bad. It’s not something you want to have happen to you!

Of course the FDA says it better than I do…

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Joyce Korvick, M.D., deputy director for safety in FDA’s Division of Gastroenterology Products. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

“Proton pump inhibitors, available by prescription and over-the-counter (OTC), work by reducing the amount of acid in the stomach. Prescription proton pump inhibitors include esomeprazole (Nexium), dexlansoprazole (Dexilant), omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), and rabeprazole (Aciphex). Prescription proton pump inhibitors are used to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus. OTC versions, used for the treatment of frequent heartburn, include omeprazole (Prilosec OTC, Zegerid OTC) and lansoprazole (Prevacid 24HR).”

Seriously? If you take Nexium or Prilosec (or any of the other proton pump inhibitors mentioned above), run this news by your doctor. These kinds of fractures are life-changing kinds of bad.

Here’s the link to the FDA article.

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